Association of NCAM1 polymorphisms with autism and parental age at conception in a Chinese Han population.

@article{Zhang2014AssociationON,
  title={Association of NCAM1 polymorphisms with autism and parental age at conception in a Chinese Han population.},
  author={Jishui Zhang and Aihua Wang and Yan A. Li and Xiaoyan Lu and Fang Wang and Fang Fang},
  journal={Genetic testing and molecular biomarkers},
  year={2014},
  volume={18 10},
  pages={690-4}
}
AIMS The neural cell adhesion molecule (NCAM) has been reported to be involved in the development of the central nervous system and its mRNA level might decrease in the serum of autistic patients. However, there was no evidence of the association of the NCAM1 gene polymorphisms with autism. In the present study, we enrolled 237 children with autism and 451 healthy control subjects. Then, we used the direct DNA sequencing for genotyping five tag single-nucleotide polymorphisms (SNPs) in the… CONTINUE READING

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