Association of NAT2 phenotype with risk of head and neck carcinoma: A meta-analysis.

@article{Zheng2012AssociationON,
  title={Association of NAT2 phenotype with risk of head and neck carcinoma: A meta-analysis.},
  author={Youyang Zheng and Yong Li and Yaoshu Teng and Zhen Zhang and Xiaolin Cao},
  journal={Oncology letters},
  year={2012},
  volume={3 2},
  pages={429-434}
}
N-acetyltransferase 2 (NAT2) is a key enzyme involved in the metabolism of xenobiotics and plays a significant role in the detoxification of numerous potential carcinogens. According to its acetylation status, NAT2 acetylator may be classified into two phenotypes, rapid and slow. Numerous studies have demonstrated that the polymorphisms of NAT2 were correlated with individual susceptibility to several malignant neoplasms, including head and neck carcinomas (HNC). However, the associations… CONTINUE READING

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