Association of N-ethylmaleimide-sensitive factor with synaptic vesicles.

  title={Association of N-ethylmaleimide-sensitive factor with synaptic vesicles.},
  author={Rong-Mou Hong and Hiroki Mori and T. Fukui and Yoshinori Moriyama and Masamitsu Futai and Akitsugu Yamamoto and Yutaka Tashiro and Mitsuo Tagaya},
  journal={FEBS letters},
  volume={350 2-3},
N-Ethylmaleimide-sensitive factor (NSF) mediates docking and/or fusion of transport vesicles in the multi-pathways of vesicular transport. NSF was highly expressed in brain and adrenal gland. Immunostaining of cerebellum with an anti-NSF monoclonal antibody showed that NSF is predominantly localized in the molecular layers and the glomeruli of the granule cell layers. This distribution coincided well with that of synaptophysin, a marker protein of synaptic vesicles. Purification and… CONTINUE READING

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