Association of Monosodium Glutamate Intake With Overweight in Chinese Adults: The INTERMAP Study

@article{He2008AssociationOM,
  title={Association of Monosodium Glutamate Intake With Overweight in Chinese Adults: The INTERMAP Study},
  author={Ka He and Liancheng Zhao and Martha L. Daviglus and Alan R Dyer and Linda Van Horn and Daniel B. Garside and Liguang Zhu and Dong-shuang Guo and Yangfeng Wu and Bei-fan Zhou and Jeremiah Stamler},
  journal={Obesity},
  year={2008},
  volume={16}
}
Animal studies indicate that monosodium glutamate (MSG) can induce hypothalamic lesions and leptin resistance, possibly influencing energy balance, leading to overweight. [] Key Method We conducted a cross-sectional study involving 752 healthy Chinese (48.7% women), aged 40-59 years, randomly sampled from three rural villages in north and south China. The great majority of participants prepared their foods at home, without use of commercially processed foods.

Consumption of monosodium glutamate in relation to incidence of overweight in Chinese adults: China Health and Nutrition Survey (CHNS).

MSG consumption was positively, longitudinally associated with overweight development among apparently healthy Chinese adults, and mixed effects models were constructed to estimate change in BMI.

Monosodium glutamate is not associated with overweight in Vietnamese adults

It was demonstrated that overweight was not associated with MSG intake in Vietnamese adults, and factors associated with overweight were age, region of residence, lifelong occupation, physical activity and intakes of energy, carbohydrates, saturated fat and animal protein.

Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population

Higher amounts of individual MSG consumption are associated with the risk of having the metabolic syndrome and being overweight independent of other major determinants.

Monosodium glutamate is not associated with obesity or a greater prevalence of weight gain over 5 years: findings from the Jiangsu Nutrition Study of Chinese adults

Findings indicate that when other food items or dietary patterns are accounted for, no association exists between MSG intake and weight gain.

Monosodium Glutamate Affects Metabolic Syndrome Risk Factors on Obese Adult Rats: A Preliminary Study

A relevant effect of MSG intake on abdominal fat and liver weight as well as liver lipid content was demonstrated in this study.

Monosodium Glutamate Intake, Dietary Patterns and Asthma in Chinese Adults

A ‘Traditional’ food pattern was positively associated with asthma among Chinese adults, and there was no significant association between MSG intake and asthma.

Monosodium glutamate is related to a higher increase in blood pressure over 5 years: findings from the Jiangsu Nutrition Study of Chinese adults

MSG intake may have independent BP-increasing effects, especially among women and those taking hypertension medications at baseline and follow-up, and in those chronically taking antihypertensive medications.

Epidemiological Studies of Monosodium Glutamate and Health

It is difficult to make a conclusion on the relation between monosodium glutamate and health in free-living subjects since from five surveys, two found no associations while three found associations, and results of these studies have been controversial.
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