Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes

@article{Gambelunghe2000AssociationOM,
  title={Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes},
  author={Giovanni Gambelunghe and Mandana Ghaderi and Anna Cosentino and Ad. Falorni and Paolo Brunetti and Al. Falorni and Carani Balaraman Sanjeevi},
  journal={Diabetologia},
  year={2000},
  volume={43},
  pages={507-514}
}
Aims/hypothesis. A distinct family of MHC genes has been identified in the class III region and denominated MHC Class I chain-related genes (MIC). The MIC-A gene is located between the TNFA and the HLA-B genes. The aim of our study was to test the association of the polymorphism of the MIC-A gene with Type I (insulin-dependent) diabetes mellitus and evaluate the interaction between MIC-A and TNFA, HLA-B, HLA-DR and HLA-DQ gene polymorphism.¶Methods. Type I diabetic (n = 95) and healthy (n = 98… CONTINUE READING
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