Association of LEP and ADIPOQ common variants with colorectal cancer in Mexican patients.

@article{PartidaPrez2010AssociationOL,
  title={Association of LEP and ADIPOQ common variants with colorectal cancer in Mexican patients.},
  author={Miriam Partida-P{\'e}rez and Mar{\'i}a de la Luz Ayala-Madrigal and Jorge Peregrina-Sandoval and Nelly Margarita Mac{\'i}as-G{\'o}mez and Jose Miguel Moreno-Ortiz and Evelia Leal-Ugarte and Mario A C{\'a}rdenas-Meza and Manuel Centeno-Flores and V{\'i}ctor Manuel Maciel-Guti{\'e}rrez and Enrique Cabrales and Sergio Cervantes-Ortiz and Melva Guti{\'e}rrez-Angulo},
  journal={Cancer biomarkers : section A of Disease markers},
  year={2010},
  volume={7 3},
  pages={117-21}
}
Leptin and adiponectin are cytokines produced by adipose tissue with opposite effects on tumor growth: the former stimulate whereas the latter inhibit it. The objective was to analyze the association of LEP A19G and ADIPOQ+45 T/G and +276 G/T polymorphisms in Mexican patients with colorectal cancer (CRC). 68 unrelated patients with CRC (study group) and 102 blood donors (control group); all subjects were Mestizos from western Mexico. The polymorphisms were established by PCR-RFLP on DNA samples… CONTINUE READING