Association of LAPTM4B gene polymorphism with breast cancer susceptibility.

  title={Association of LAPTM4B gene polymorphism with breast cancer susceptibility.},
  author={Meirong Fan and Ye Liu and Rouli Zhou and Qingyun Zhang},
  journal={Cancer epidemiology},
  volume={36 4},
BACKGROUND Lysosome associated protein transmembrane 4 beta (LAPTM4B) was a cancer-associated gene that is mapped to chromosome 8q22 with seven exons and six introns. LAPTM4B gene polymorphism has been reported to be significantly associated with susceptibility of several solid tumors. METHODS We performed a case-control study was to investigate the association between LAPTM4B polymorphism and the risk of breast cancer in 732 breast cancer patients and 649 controls. RESULTS A significant… CONTINUE READING