Association of Increased Serum ACE Activity with Logical Memory Ability in Type 2 Diabetic Patients with Mild Cognitive Impairment

@inproceedings{Tian2016AssociationOI,
  title={Association of Increased Serum ACE Activity with Logical Memory Ability in Type 2 Diabetic Patients with Mild Cognitive Impairment},
  author={Sai Tian and Jing Han and Rong Huang and Wenqing Xia and Jie Sun and Rongrong Cai and Xue Dong and Yanjue Shen and Shaohua Wang},
  booktitle={Front. Behav. Neurosci.},
  year={2016}
}
Background: Angiotensin-converting enzyme (ACE) is involved in the chronic complications of type 2 diabetes mellitus (T2DM) and Alzheimer's disease. This study aimed to assess the pathogenetic roles of ACE and the genetic predisposition of its insertion/deletion (I/D) polymorphism in mild cognitive impairment (MCI) among T2DM patients. Methods: A total of 210 T2DM patients were enrolled. Among these patients, 116 satisfied the MCI diagnostic criteria and 94 exhibited healthy cognition. The… CONTINUE READING
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