Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.

@article{Akuta2012AssociationOI,
  title={Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.},
  author={Norio Akuta and Fumitaka Suzuki and Yuya Seko and Yusuke Kawamura and Hitomi Sezaki and Yoshiyuki Suzuki and Tetsuya Hosaka and Masahiro Kobayashi and Mariko Kobayashi and Satoshi Saitoh and Yasuji Arase and Kenji Ikeda and Hiromitsu Kumada},
  journal={Journal of medical virology},
  year={2012},
  volume={84 10},
  pages={
          1593-9
        }
}
The impacts of IL28B genotype to treatment response of hepatitis C virus (HCV) genotype 2 are still not clear. A total of 381 consecutive Japanese patients infected with HCV genotype 2, who could complete combination therapy with interferon (IFN) plus ribavirin for 24 weeks, were evaluated to investigate pretreatment predictors. Patients, who could not achieve sustained virological response at the first course of 24-week IFN plus ribavirin, were recruited into the study protocol of total 48… CONTINUE READING

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