Association of ICAM-1 with the cytoskeleton in rat alveolar epithelial cells in primary culture.

@article{Barton1996AssociationOI,
  title={Association of ICAM-1 with the cytoskeleton in rat alveolar epithelial cells in primary culture.},
  author={W W Barton and Steven E. Wilcoxen and Paul Christensen and Robert Paine},
  journal={The American journal of physiology},
  year={1996},
  volume={271 5 Pt 1},
  pages={L707-18}
}
Intercellular adhesion molecule-1 ICAM-1) is a transmembrane adhesion protein that is expressed constitutively on the apical surface of type I cells in vivo and on type II cells in vitro as they spread in culture, assuming type I cell-like characteristics. To investigate the possible interaction of ICAM-1 with the alveolar epithelial cell cytoskeleton, rat type II cells in primary culture were extracted with nonionic detergent, and residual ICAM-1 associated with the cytoskeletal remnants was… CONTINUE READING