Association of HLA mismatch with death with a functioning graft after kidney transplantation: a collaborative transplant study report.

@article{Opelz2012AssociationOH,
  title={Association of HLA mismatch with death with a functioning graft after kidney transplantation: a collaborative transplant study report.},
  author={Gerhard Opelz and Bernd D{\"o}hler},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 11},
  pages={
          3031-8
        }
}
HLA mismatches may correlate with risk of death with a functioning graft (DWFG) because of requirement for higher immunosuppression doses and more antirejection therapy. Deceased-donor kidney transplants (n = 177 584) performed 1990-2009 and reported to the Collaborative Transplant Study were analyzed. The incidence of DWFG was found to be 4.8% during year 1 posttransplant and 7.7% during years 2-5 (Kaplan-Meier estimates). Most frequent causes of DWFG were infection, cardiovascular disease and… CONTINUE READING
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