Association of HLA-DQA1 and -DQB1 alleles with type I diabetes in Arabs: a meta-analyses.

  title={Association of HLA-DQA1 and -DQB1 alleles with type I diabetes in Arabs: a meta-analyses.},
  author={Abdul Rezzak Hamzeh and Pratibha P Nair and Najib Al-Khaja and Mahmoud T Al Ali},
  journal={Tissue antigens},
  volume={86 1},
This study aimed at assessing the nature and significance of associations between various alleles of HLA-DQA1, HLA-DQB1, and type I diabetes (T1D) in Arab populations. Evidence from literature (published before 20 April 2015) was amassed and analysed through multiple meta-analyses, which yielded effect summary odds ratios and 95% confidence intervals for 24 alleles and 4 haplotypes. A total of 1273 cases and 1747 controls from 16 studies were analysed. High levels of significance were obtained… CONTINUE READING


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