Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic Asian Indian patients.

@article{Kumaramanickavel2002AssociationOG,
  title={Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic Asian Indian patients.},
  author={Govindasamy Kumaramanickavel and Vedam Lakshmi Ramprasad and Sarangapani Sripriya and Neelam Kumari Upadyay and Pradeep George Paul and Tarun Sharma},
  journal={Journal of diabetes and its complications},
  year={2002},
  volume={16 6},
  pages={391-4}
}
AIM/HYPOTHESIS The binding of advanced glycation end products (AGE) to the receptor induces cellular oxidative stress and vascular dysfunction and this is implicated in the pathogenesis of diabetic retinopathy (DR). This study aims to investigate the frequency of Gly82Ser polymorphism in exon 3 of the receptor for AGE (RAGE) gene and its association with DR in Asian Indian patients who have type II diabetes. METHODS 200 Asian Indian patients with at least 15-year duration of type II diabetes… CONTINUE READING

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