Association of Germfree Mice with Bacteria Isolated from Normal Mice

  title={Association of Germfree Mice with Bacteria Isolated from Normal Mice},
  author={Russell W. Schaedler and Ren{\'e} J. Dubos and Richard L. Costello},
  journal={The Journal of Experimental Medicine},
  pages={77 - 82}
Germfree mice were given food contaminated with pure cultures of various bacterial species isolated from ordinary healthy mice. The cultures were given singly, or in association, or consecutively at weekly intervals. Whatever the technique of administration, the lactobacilli and anaerobic streptococci immediately established themselves throughout the gastrointestinal tract, and became closely associated with the walls of the organs. In contrast, the organisms of the bacteroides group were found… CONTINUE READING
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