Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing

@inproceedings{OConnell2013AssociationOG,
  title={Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing},
  author={Garret O’Connell and Heather C Whalley and Prerona Mukherjee and Andrew C. Stanfield and Christian Montag and Jeremy Hall and Martin Reuter},
  year={2013}
}
Evidence supports the involvement of oxytocin in social behavior. The oxytocin receptor gene (OXTR) has been associated with differences in social brain function and risk for autism. Motivated by recent work, we investigated the effect of variation in the common functional rs2268498 T/C polymorphism in the promoter region of OXTR on neural responses to fear expressions. 46 healthy subjects were divided into genotype groups of C carriers (n = 32) and TT homozygous (n = 14) and neural activity… CONTINUE READING
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