Association of Genetic Polymorphisms in TNF and MIF Gene with the Risk of Primary Dysmenorrhea

  title={Association of Genetic Polymorphisms in TNF and MIF Gene with the Risk of Primary Dysmenorrhea},
  author={Hatice Yılmaz Doğru and Asker Zeki Ozsoy and Nevin Karakuş and Ilhan Bahri Delibas and Çigdem Kunt Isguder and Serbulent Yigit},
  journal={Biochemical Genetics},
Primary dysmenorrhea, which affects 90 % of adolescent girls and more than 50 % of menstruating women worldwide, is characterized by recurrent pain during menses in the absence of a detectable organic disease. The aim of this study is to assess the association between MIF −173 and TNF −308 genetic polymorphisms and the clinical features of primary dysmenorrhea. The study population comprised 154 unrelated female patients with clinical diagnosis of dysmenorrhea, and a total of 144 control… 
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