Association of GSTP 1 and XRCC 1 gene polymorphisms with clinical outcome of advanced non-small cell lung cancer patients with cisplatin-based chemotherapy

@inproceedings{Han2015AssociationOG,
  title={Association of GSTP 1 and XRCC 1 gene polymorphisms with clinical outcome of advanced non-small cell lung cancer patients with cisplatin-based chemotherapy},
  author={Bateer Han and Zhanlin Guo and Yingjiang Ma and Shirong Kang and Yufei Wang and Qiyou Wei and Xu Wu},
  year={2015}
}
We investigated the association between the clinical outcome and GSTP1 and XRCC1 gene polymorphisms in advanced NSCLC patients with cisplatin-based chemotherapy. We prospectively recruited 325 NSCLC patients between January 2010 and January 2014. Genotypes of GSTP1 A313G, XRCC1 Arg194Trp, Arg280His and Arg399Gln were conducted using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) assay. AG and GG genotypes of GSTP1 A313G were correlated with a higher CR + PR when… CONTINUE READING
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Biomarkers as prognostic factors for cN2 or 3 non-small cell lung GSTP1 and XRCC1 polymorphisms and clinical outcome of advanced NSCLC

  • H Yokomise, D Liu, +4 authors N. Nakashima
  • Int J Clin Exp Pathol
  • 2015
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