Association of Epstein-Barr virus genome with mixed cellularity and cellular phase nodular sclerosis Hodgkin's disease subtypes.

@article{Boiocchi1992AssociationOE,
  title={Association of Epstein-Barr virus genome with mixed cellularity and cellular phase nodular sclerosis Hodgkin's disease subtypes.},
  author={Mauro Boiocchi and Valli De Re and Riccardo Dolcetti and Antonino Carbone and Aldo Scarpa and Fabio Menestrina},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={1992},
  volume={3 4},
  pages={307-10}
}
Association of Epstein-Barr virus (EBV) genome with Hodgkin's disease (HD) histological subtypes was investigated using the polymerase chain reaction (PCR). A highly significant association of EBV genome with the mixed cellularity (MC) subtype (10 positive out of 15 cases; 66%) was observed, suggesting a possible etiopathogenetic role of EBV in the induction of this subset. By contrast, a markedly lower frequency of association with EBV genome was found in nodular sclerosis (NS) (12 positive… CONTINUE READING
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