Association of EGFR expression level and cetuximab activity in patient-derived xenograft models of human non-small cell lung cancer.

Abstract

PURPOSE To explore in a panel of patient-derived xenograft models of human non-small cell lung cancer (NSCLC) whether high EGFR expression, was associated with cetuximab activity. EXPERIMENTAL DESIGN NSCLC patient-derived xenograft models (n=45) were implanted subcutaneously into panels of nude mice and randomization cohorts were treated with either… (More)
DOI: 10.1158/1078-0432.CCR-13-3385

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