Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome

@article{Nordmark2011AssociationOE,
  title={Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sj{\"o}gren's syndrome},
  author={Gunnel Nordmark and Gudlaug T Kristjansdottir and Elke Theander and Silke Appel and Per Eriksson and L Vasaitis and Marika Kvarnstr{\"o}m and Nicolas Delaleu and Per E Lundmark and Anders Lundmark and Christopher Sjӧwall and Johan G Brun and Malin Viktoria Jonsson and Erna Harboe and Lasse Gunnar G\oransson and Svein Joar Augl{\ae}nd Johnsen and Peter S{\"o}derkvist and M-L Eloranta and Gunnar Alm and Eva Baecklund and Marie Wahren-Herlenius and Roald Omdal and Lars R{\"o}nnblom and Roland Jonsson and A-C Syv{\"a}nen},
  journal={Genes and Immunity},
  year={2011},
  volume={12},
  pages={100-109}
}
We performed a candidate gene association study in 540 patients with primary Sjögren's Syndrome (SS) from Sweden (n=344) and Norway (n=196) and 532 controls (n=319 Swedish, n=213 Norwegian). A total of 1139 single-nucleotide polymorphisms (SNPs) in 84 genes were analyzed. In the meta-analysis of the Swedish and Norwegian cohorts, we found high signals for association between primary SS and SNPs in three gene loci, not previously associated with primary SS. These are the early B-cell factor 1… CONTINUE READING

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