Association of DNA Methylation with Acute Mania and Inflammatory Markers

Abstract

In order to determine whether epigenetic changes specific to the manic mood state can be detected in peripheral blood samples we assayed DNA methylation levels genome-wide in serum samples obtained from 20 patients hospitalized for mania and 20 unaffected controls using the Illumina 450K methylation arrays. We identified a methylation locus in the CYP11A1… (More)
DOI: 10.1371/journal.pone.0132001

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