Association of Carotid Arterial Resistive Indices and Intima Media Thickness (IMT) With Glycemic Status in Type 2 Diabetic Patients

  • Perumal .K.K, Balu Mahendran.K
  • Published 2015

Abstract

Background: Chronic hyperglycemia causes oxidative stress, impairs endothelial function, facilitates monocyte adhesion to endothelial cells and thickens intima media contributing to development of atherosclerosis. The resistive index and intima-media thickness (IMT) of the carotid artery are sonographic parameters that depend on the degree of atherosclerosis. Aim: The aim of this study was to evaluate the association of carotid arterial resistive index, IMT with glycemic status in type 2 diabetic patients. Materials and methods: Thirty five type 2 diabetic patients with more than 5 year diabetic duration in the age group of 35 to 60 years were selected for this study, 20 age matched healthy individuals were selected as control group. Common carotid artery resistive index, IMT and glycated hemoglobin (HbA1C) were analyzed by conventional standardized methods. Results: The mean levels of Carotid arterial resistive index, IMT are significantly increased in diabetic patients. Common carotid artery resistive index and intima media thickness positively correlated with HbA1c. Conclusion: Evaluation of Carotid arterial resistive index and IMT could be potentially useful diagnostic markers for the assessment of atherosclerotic changes and endothelial dysfunction as a consequence of chronic hyperglycemia in diabetic patients.

Cite this paper

@inproceedings{KK2015AssociationOC, title={Association of Carotid Arterial Resistive Indices and Intima Media Thickness (IMT) With Glycemic Status in Type 2 Diabetic Patients}, author={Perumal .K.K and Balu Mahendran.K}, year={2015} }