Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer.

@article{Kodama2007AssociationOC,
  title={Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer.},
  author={Junichi Kodama and Hasengaowa and Tomoyuki Kusumoto and Naruhito Seki and Tamaki Matsuo and Yojiro Ojima and Kazuto Nakamura and Atsushi Hongo and Yasushi Hiramatsu},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2007},
  volume={18 1},
  pages={70-6}
}
BACKGROUND The chemokine receptors CXCR4 and CCR7 have been suggested to play an important role in cancer invasion and metastasis. The expression of these receptors in human cervical cancer, however, has seldom been characterized. PATIENTS AND METHODS We investigated the expression of CXCR4 and CCR7 in cervical cancer specimens and determined the association between their expression and the clinicopathological features observed, including patient outcome. RESULTS CXCR4 expression was… CONTINUE READING

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