Association of CHRM2 with IQ: Converging Evidence for a Gene Influencing Intelligence

  title={Association of CHRM2 with IQ: Converging Evidence for a Gene Influencing Intelligence},
  author={Danielle M. Dick and F. Aliev and J. Kramer and Jen C. Wang and A. Hinrichs and S. Bertelsen and S. Kuperman and M. Schuckit and John I Nurnberger and H. Edenberg and B. Porjesz and H. Begleiter and V. Hesselbrock and A. Goate and L. Bierut},
  journal={Behavior Genetics},
  • Danielle M. Dick, F. Aliev, +12 authors L. Bierut
  • Published 2007
  • Psychology, Medicine
  • Behavior Genetics
  • The cholinergic neurotransmitter system is thought to be involved in many aspects of memory, attention, and higher cognition. In the Collaborative Study on the Genetics of Alcoholism (COGA) sample, we have previously reported linkage and association to the cholinergic muscarinic 2 receptor gene (CHRM2) on chromosome 7 with evoked EEG oscillations (Jones et al. 2004), providing evidence that this gene may be involved in human brain dynamics and cognition. In addition, a small number of genetic… CONTINUE READING
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