Association of CETP Taq1B and -629C > A polymorphisms with coronary artery disease and lipid levels in the multi-ethnic Singaporean population

@inproceedings{Lu2012AssociationOC,
  title={Association of CETP Taq1B and -629C > A polymorphisms with coronary artery disease and lipid levels in the multi-ethnic Singaporean population},
  author={Yongjian Lu and Naeimeh Tayebi and Hongzhe Li and N. Banerjee Saha and Hongyuan Yang and Chew-Kiat Heng},
  booktitle={Lipids in Health and Disease},
  year={2012}
}
Hyperlipidaemia is a major risk factor for coronary artery disease (CAD) and cholesteryl ester transfer protein (CETP) gene polymorphisms are known to be associated with lipid profiles. In this study, we investigated the association of two polymorphisms in the CETP, Taq1B (rs708272) and -629C > A (rs1800775), with CAD and lipid levels HDL-C in 662 CAD + cases and 927 controls from the Singapore population comprising Chinese, Malays and Indians. TaqB2 frequency was significantly lowest in the… CONTINUE READING