Association of CD8+ T cell infiltration in oesophageal carcinoma lesions with human leucocyte antigen (HLA) class I antigen expression and survival.

@article{Tsuchikawa2011AssociationOC,
  title={Association of CD8+ T cell infiltration in oesophageal carcinoma lesions with human leucocyte antigen (HLA) class I antigen expression and survival.},
  author={Takahiro Tsuchikawa and Hiroshi Ikeda and Y Cho and Masaki Miyamoto and Toshiaki Shichinohe and Satoshi Hirano and Satoshi Kondo},
  journal={Clinical and experimental immunology},
  year={2011},
  volume={164 1},
  pages={50-6}
}
Oesophageal cancer is one of the most aggressive tumours with a poor prognosis. However, little is known about the immune response in the tumour microenvironment. To investigate the role of immunosurveillance in the clinical course of oesophageal squamous cell carcinoma, 98 formalin-fixed, paraffin-embedded primary tumours were analysed using immunohistochemical methods for human leucocyte antigen (HLA) class I heavy chain and β2-microglobulin expression and for CD4-, CD8- and CD57-positive… CONTINUE READING

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