Association of CD20+ infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts.

@article{Hippen2005AssociationOC,
  title={Association of CD20+ infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts.},
  author={Benjamin E Hippen and Angelo M Demattos and William J. Cook and Clifton E Kew and Robert S. Gaston},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2005},
  volume={5 9},
  pages={2248-52}
}
We undertook a study to ascertain the relationship between the presence of CD20-positive B-lymphocytes in renal allografts undergoing acute cellular rejection and graft survival. We identified 27 patients transplanted between January 1, 1998 and December 31, 2001, with biopsy-proven Banff 1-A or Banff 1-B rejection in the first year after transplantation, and stained the specimens for CD20 and C4d. At least 4 years of follow-up data were available for each patient studied. Six patients had CD20… CONTINUE READING

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