Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan

@article{Tan2006AssociationOC,
  title={Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan},
  author={Choon-Yee Tan and Yi-Lin Chen and Lawrence Shih-Hsin Wu and Chai-Fan Liu and Wen-Tsan Chang and Jiu-yao Wang},
  journal={Journal of Human Genetics},
  year={2006},
  volume={51},
  pages={59-67}
}
AbstractCD14 is responsible for environmental lipopolysaccharide recognition and is a positional candidate gene for allergy. We hypothesized that genetic polymorphisms in the promoter region of the CD14 gene may be associated with Dermatophagoides pteronysinnus (Der p) allergen sensitization in children. Three single nucleotide polymorphisms (SNPs) of the CD14 promoter region, C(−159)T, A(−1,145)G, and G(−1,359)T were genotyped, and analyzed in 240 randomized case-control school-age children in… CONTINUE READING
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