Association of C609T-Inborn Polymorphism of NAD(P)H: Quinone Oxidoreductase 1 with the Risk of Bronchopulmonary Dysplasia in Preterm Neonates.

@article{Gavrili2016AssociationOC,
  title={Association of C609T-Inborn Polymorphism of NAD(P)H: Quinone Oxidoreductase 1 with the Risk of Bronchopulmonary Dysplasia in Preterm Neonates.},
  author={Stavroula Gavrili and Sophia Zachaki and Aggeliki Daraki and Elena Polycarpou and Kalliopi N. Manola and Chryssa Stavropoulou and Constantina Sambani and George Baroutis},
  journal={American journal of perinatology},
  year={2016},
  volume={33 6},
  pages={535-9}
}
UNLABELLED Objectives In bronchopulmonary dysplasia (BPD), direct exposure to oxygen therapy can damage the pulmonary epithelium via oxidative stress. The NAD(P)H quinone oxidoreductase 1 (NQO1) enzyme detoxifies genotoxic products of oxidative stress. The corresponding gene is subject to an inactivating single-nucleotide polymorphism (C(609)T), which… CONTINUE READING