Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease

  title={Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease},
  author={Belinda T. Lee and Faheemuddin Azher Ahmed and L. Gabriel Navar L. Lee Hamm and Federico J. Teran and Chung-Shiuan Chen and Yanxi Liu and Kamal Shah and N M El Rifai and Vecihi Batuman and Eric E. Simon and Jiang He and Jing Chen},
  booktitle={BMC nephrology},
BACKGROUND We studied the association of inflammatory biomarkers including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) with chronic kidney disease (CKD). METHODS We conducted a case-control study among 201 CKD patients and 201 community-based controls in the greater New Orleans area. CKD was defined as estimated-glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2) or albuminuria ≥30 mg/24-h. Serum CRP, TNF-α, and IL-6 were measured using standard… CONTINUE READING
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