Association of BH3 interacting domain death agonist (BID) gene polymorphisms with proteinuria of immunoglobulin A nephropathy.

@article{Park2014AssociationOB,
  title={Association of BH3 interacting domain death agonist (BID) gene polymorphisms with proteinuria of immunoglobulin A nephropathy.},
  author={Hae Jeong Park and Jong Woo Kim and Byoung-Soo Cho and Joo-Ho Chung},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={2014},
  volume={74 4},
  pages={
          329-35
        }
}
BACKGROUND Apoptosis plays an important role in the mechanism regulating the development of glomerulonephritis. We investigated whether polymorphisms of apoptotic genes such as B-cell CLL/lymphoma 2 (BCL2), BH3-interacting domain death agonist (BID), and caspase 8 (CASP8) were associated with immunoglobulin A nephropathy (IgAN) and with the clinical phenotypes of IgAN patients. METHODS We genotyped promoter and coding region single nucleotide polymorphisms (SNPs) (rs2279115 and rs1801018 for… CONTINUE READING