Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.

  title={Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.},
  author={Marta Ribas{\'e}s and M{\'o}nica Gratac{\'o}s and Fernando Fern{\'a}ndez-Aranda and Laura Bellodi and Claudette Boni and Marija Anderluh and Maria Cristina Cavallini and Elena Cellini and Daniela di Bella and Stefano Erzegovesi and Christine Foulon and Mojca Gabrovsek and Philip Gorwood and Johannes Hebebrand and Anke Hinney and Jo Holliday and Xun Hu and Andreas Karwautz and Am{\'e}lie Kipman and Radovan Komel and Benedetta Nacmias and Helmut Remschmidt and Valdo Ricca and Sandro Sorbi and Gudrun Wagner and Janet Treasure and David A. Collier and Xavier Estivill},
  journal={Human molecular genetics},
  volume={13 12},
Several genes with an essential role in the regulation of eating behavior and body weight are considered candidates involved in the etiology of eating disorders (ED), but no relevant susceptibility genes with a major effect on anorexia nervosa (AN) or bulimia nervosa (BN) have been identified. Brain-derived neurotrophic factor (BDNF) has been implicated in the regulation of food intake and body weight in rodents. We previously reported a strong association of the Met66 allele of the Val66Met… CONTINUE READING


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