Association of Activated T Cells and Dendritic Cells in Atherosclerotic Lesions in Apo E-Deficient Mice


Background: Antigen-specific T cell activation plays an important role in the initiation and progression of atherosclerosis. T cell activation can occur only if antigen is presented to T cells by antigenpresenting cells expressing co-stimulatory signal molecules. Apo E-deficient mice are widely used for investigating the role of antigen-presenting dendritic… (More)


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