Association of ADHD and Celiac Disease: What Is the Evidence? A Systematic Review of the Literature

@article{Ertrk2016AssociationOA,
  title={Association of ADHD and Celiac Disease: What Is the Evidence? A Systematic Review of the Literature},
  author={Emine Yurdakul Ert{\"u}rk and Sara Wouters and Lindita Imeraj and Annik Lampo},
  journal={Journal of Attention Disorders},
  year={2016},
  volume={24},
  pages={1371 - 1376}
}
Objective: This article tries to answer the question whether or not there is evidence for a relationship between celiac disease (CD) and ADHD. A review of the current literature on this topic is provided. Method: PUBMED/MEDLINE, Web of Science, and Google scholar were searched to include all published trials on ADHD and CD (no date limitation, both noncontrolled and controlled trials). In addition, the reference list of included studies was screened to find other relevant articles. Results… Expand
Prevalence of Celiac Disease Is Not Increased in ADHD Sample
TLDR
It is concluded that there are not enough data to support screening for CD and the introduction of a gluten-free diet in children with ADHD unless there are additional indications. Expand
Attention deficit hyperactivity disorder and gastrointestinal morbidity in a large cohort of young adults
BACKGROUND Although the association of attention deficit hyperactivity disorder (ADHD) with psychiatric disorders is well known, its association with somatic diseases is unclear. Only few studiesExpand
Comorbidities in Childhood Celiac Disease: A Phenome Wide Association Study Using the Electronic Health Record
TLDR
This is the first PheWAS of CD to confirm a significant association of eosinophilic disorders of the esophagus with CD in a controlled study and validate associations at the population level. Expand
Gluten Intolerance and Neurodevelopmental Disorders: Is Nitric Oxide the Common Biomarker Linking These Conditions?
  • K. Fluegge
  • Medicine
  • Annals of Nutrition and Metabolism
  • 2016
TLDR
The purpose of this correspondence is to highlight this biochemical connection between celiac disease and ADHD/ASD so as to identify the clinical populations who may realize the greatest benefit of these dietary approaches, while minimizing any potential risk of nutrient deficiencies. Expand
Attention deficit and hyperactivity disorder symptoms respond to gluten-free diet in patients with coeliac disease
TLDR
Prior to treatment, coeliac disease patients reported significantly more symptoms than healthy controls on ASRS and HADS, and the differences disappeared after a minimum of 12 months on a gluten-free diet. Expand
Non-mental diseases associated with ADHD across the lifespan: Fidgety Philipp and Pippi Longstocking at risk of multimorbidity?
TLDR
It is concluded that non-mental diseases are common in ADHD and vice versa and add to the disease burden of the patient across the lifespan. Expand
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TLDR
There is reasonably robust evidence for the use of some dietary and nutritional approaches such as reduction of food dyes and supplementing with essential fatty acids and broad spectrum micronutrients. Expand
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TLDR
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A Review of Psychiatric Disorders Associated with Celiac Disease
TLDR
Psychiatric disorders that occur in association with Celiac Disease are examined, pathophysiological mechanisms that may be responsible for these comorbid conditions are studied, and areas of research are suggested that could both improve understanding and reveal potential new treatments for these psychiatric disorders. Expand
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