Association of 5-HT2A receptor gene polymorphisms with gastrointestinal disorders in Egyptian children with autistic disorder.

@article{Abdelrahman2015AssociationO5,
  title={Association of 5-HT2A receptor gene polymorphisms with gastrointestinal disorders in Egyptian children with autistic disorder.},
  author={Hadeel M. Abdelrahman and Laila Metwaly Sherief and Ashgan A Alghobashy and Sanaa M Abdel Salam and Haitham M. Hashim and Nelly R. Abdel Fattah and Randa H. Mohamed},
  journal={Research in developmental disabilities},
  year={2015},
  volume={36C},
  pages={
          485-490
        }
}
Gastrointestinal disturbances (GID) are frequently reported in children with autism spectrum disorders (ASD). Recently, mounting evidence suggests that there may be a genetic link for autism with gastrointestinal disturbances. We aimed to investigate whether there were any association between the -1438A/G, 102T/C and His452Tyr polymorphisms of the serotonin 2A receptor gene (5-HT2A) in Egyptian children with ASD and GID. Eighty children with autistic disorder and 100 healthy control children… CONTINUE READING
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