Association of 3'----5' exodeoxyribonuclease activity with DNA replitase complex from S-phase Chinese hamster embryo fibroblast cells.

@article{Hammond1989AssociationO3,
  title={Association of 3'----5' exodeoxyribonuclease activity with DNA replitase complex from S-phase Chinese hamster embryo fibroblast cells.},
  author={R. A. Hammond and M. Miller and M. S. Gray and G. Reddy},
  journal={Experimental cell research},
  year={1989},
  volume={183 2},
  pages={
          284-93
        }
}
  • R. A. Hammond, M. Miller, +1 author G. Reddy
  • Published 1989
  • Biology, Medicine
  • Experimental cell research
    • DNA replitase has been described as a complex of enzymes/proteins that are associated with both DNA precursor biosynthesis and DNA replication in mammalian cells [Reddy, G. P. V., and Pardee, A. B. (1980) Proc. Natl. Acad. Sci. USA 77, 3312-3316]. We demonstrate for the first time a 3'----5' exodeoxyribonuclease activity is associated with the replitase complex. As much as 60% of this exonuclease activity was similar to that associated with DNA polymerase delta based upon its sensitivity to… CONTINUE READING
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