Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer

Abstract

γH2AX plays a role in DNA damage response signaling and facilitates the repair of DNA double strand breaks. However, it remains unknown whether constitutive tumor γH2AX expression is associated with treatment outcome in patients. γH2AX status was detected in primary tumors from 24% of 826 patients with stage I, II and III breast cancer by… (More)
DOI: 10.7150/thno.19102

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