Association mapping via regularized regression analysis of single-nucleotide-polymorphism haplotypes in variable-sized sliding windows.

Abstract

Large-scale haplotype association analysis, especially at the whole-genome level, is still a very challenging task without an optimal solution. In this study, we propose a new approach for haplotype association analysis that is based on a variable-sized sliding-window framework and employs regularized regression analysis to tackle the problem of multiple… (More)

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@article{Li2007AssociationMV, title={Association mapping via regularized regression analysis of single-nucleotide-polymorphism haplotypes in variable-sized sliding windows.}, author={Yi Li and Wing-Kin Sung and Jian Liu}, journal={American journal of human genetics}, year={2007}, volume={80 4}, pages={705-15} }