Association between vitamin D receptor gene polymorphisms and susceptibility to chronic kidney disease and periodontitis.

@article{Souza2007AssociationBV,
  title={Association between vitamin D receptor gene polymorphisms and susceptibility to chronic kidney disease and periodontitis.},
  author={Cleber Machado de Souza and Ana Paula Ribeiro Braosi and S{\^o}nia Mara Luczyszyn and Andr{\'e}a Rodrigues {\'A}vila and Rui Barbosa de Brito and S{\'e}rgio Aparecido Ign{\'a}cio and Christian Macagnan Probst and Miguel Carlos Riella and Vanessa Santos Sotomaior and Marcelo T{\'a}vora Mira and Roberto Fl{\'a}vio Silva Pecoits-Filho and Paula Cristina Trevilatto},
  journal={Blood purification},
  year={2007},
  volume={25 5-6},
  pages={411-9}
}
BACKGROUND/AIMS Chronic kidney disease (CKD) and periodontitis (PD) are serious public-health concerns. Vitamin D is a fat-soluble steroid hormone that interacts with its nuclear receptor (VDR) to regulate a variety of biological processes, such as bone metabolism, immune response modulation and transcription of several genes involved in CKD and PD disease mechanisms. The aim of this work was to investigate the association between polymorphisms in the VDR gene and end-stage renal disease (ESRD… CONTINUE READING
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