Association between vitamin D receptor gene polymorphisms and response to treatment of pulmonary tuberculosis.

@article{Roth2004AssociationBV,
  title={Association between vitamin D receptor gene polymorphisms and response to treatment of pulmonary tuberculosis.},
  author={Daniel Eugen Roth and Giselle M. Soto and Fanny Arenas and Christian T Bautista and Jaime A. Riera Ortiz and Richard D Rodriguez and Lilia Cabrera and Robert H. Gilman},
  journal={The Journal of infectious diseases},
  year={2004},
  volume={190 5},
  pages={
          920-7
        }
}
BACKGROUND Polymorphisms in the gene that encodes the vitamin D receptor (VDR) may influence the host response to Mycobacterium tuberculosis infection. METHODS In a Peruvian community with a high incidence of tuberculosis (TB), VDR TaqI and FokI polymorphisms were compared among 103 patients with pulmonary TB and 206 matched healthy control subjects. Associations of VDR polymorphisms with treatment outcome were analyzed among 78 patients undergoing treatment of pulmonary TB. RESULTS Sputum… CONTINUE READING

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