Association between vitamin D receptor gene polymorphism and Alzheimer's disease.

  title={Association between vitamin D receptor gene polymorphism and Alzheimer's disease.},
  author={Duygu Gezen-Ak and Erdinç Dursun and Turan Ertan and Hasmet Ayhan Hanagasi and Hakan G{\"u}rvit and Murat Emre and Engin Eker and M Ikbal Ozt{\"u}rk and Funda Engin and Selma Yilmazer},
  journal={The Tohoku journal of experimental medicine},
  volume={212 3},
Vitamin D(3) is known to be involved in neuroprotection and exert its neuroprotective effects by modulating neuronal calcium homeostasis and production of neurotrophins. The single nucleotide polymorphisms (SNP) in vitamin D receptor (VDR) gene which can influence the affinity of vitamin D(3) to its receptor may be related to neurodegenerative diseases and neuronal damage by altering the vitamin D-mediated pathways. In this study, our aim was to determine whether there is an association between… CONTINUE READING
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