Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations.

@article{Konings2007AssociationBV,
  title={Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations.},
  author={Annelies Konings and Lut Van Laer and Malgorzata Pawelczyk and Per-Inge Carlsson and Marie-Louise Bondeson and Elżbieta Rajkowska and Adam Dudarewicz and Ann Vandevelde and Erik Frans{\'e}n and Jeroen R Huyghe and Erik Borg and Mariola Śliwińska-Kowalska and Guy Van Camp},
  journal={Human molecular genetics},
  year={2007},
  volume={16 15},
  pages={
          1872-83
        }
}
Noise-induced hearing loss (NIHL) is an important occupational hazard that results from an interaction between genetic and environmental factors. Although the environmental risk factors have been studied quite extensively, little is known about the genetic factors. On the basis of multiple studies, it was proposed that oxidative stress plays an important role in the development of NIHL. Here, we investigated whether variations (single nucleotide polymorphisms; SNPs) in the catalase gene (CAT… CONTINUE READING

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