Association between tumor necrosis factor-α promoter −308 A/G, −238 A/G, interleukin-6 −174 G/C and −572 G/C polymorphisms and periodontal disease: a meta-analysis

@article{Song2013AssociationBT,
  title={Association between tumor necrosis factor-α promoter −308 A/G, −238 A/G, interleukin-6 −174 G/C and −572 G/C polymorphisms and periodontal disease: a meta-analysis},
  author={Gwan Gyu Song and Sung Jae Choi and Jong Dae Ji and Young Ho Lee},
  journal={Molecular Biology Reports},
  year={2013},
  volume={40},
  pages={5191-5203}
}
The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) promoter polymorphisms confer susceptibility to periodontitis in ethnically different populations. A literature search was performed using PubMed and Embase and a meta-analysis of the identified studies was conducted to explore the associations between TNF-α −308 A/G, −238 A/G, IL-6 promoter −174 G/C and −572 G/C polymorphisms and periodontitis. Seventeen comparison studies for the TNF-α −308… CONTINUE READING
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