Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol.

@article{Puskarich2011AssociationBT,
  title={Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol.},
  author={Michael A Puskarich and Stephen W Trzeciak and Nathan I Shapiro and Ryan Arnold and James M Horton and Jonathan R. Studnek and Jeffrey A. Kline and Alan E. Jones},
  journal={Critical care medicine},
  year={2011},
  volume={39 9},
  pages={
          2066-71
        }
}
OBJECTIVE We sought to determine the association between time to initial antibiotics and mortality of patients with septic shock treated with an emergency department-based early resuscitation protocol. DESIGN Preplanned analysis of a multicenter randomized controlled trial of early sepsis resuscitation. SETTING Three urban U.S. emergency departments. PATIENTS Adult patients with septic shock. INTERVENTIONS A quantitative resuscitation protocol in the emergency department targeting three… CONTINUE READING
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