Association between the surfactant protein A (SP-A) gene locus and respiratory-distress syndrome in the Finnish population.

@article{Rmet2000AssociationBT,
  title={Association between the surfactant protein A (SP-A) gene locus and respiratory-distress syndrome in the Finnish population.},
  author={Mika R{\"a}met and Rutva Haataja and Riitta Marttila and Joanna Floros and Mikko K. Hallman},
  journal={American journal of human genetics},
  year={2000},
  volume={66 5},
  pages={1569-79}
}
Respiratory-distress syndrome (RDS) in the newborn is a major cause of neonatal mortality and morbidity. Although prematurity is the most-important risk factor for RDS, the syndrome does not develop in many premature infants. The main cause of RDS is a deficiency of pulmonary surfactant, which consists of phospholipids and specific proteins. The genes underlying susceptibility to RDS are insufficiently known. The candidate-gene approach was used to study the association between the surfactant… CONTINUE READING

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