Corpus ID: 75351494

Association between the matrix metalloproteinase 3 promoter 5A/6A polymorphism and essential hypertension

@article{Hua2007AssociationBT,
  title={Association between the matrix metalloproteinase 3 promoter 5A/6A polymorphism and essential hypertension},
  author={Ma Hua},
  journal={Journal of Clinical Internal Medicine},
  year={2007}
}
  • Ma Hua
  • Published 2007
  • Medicine
  • Journal of Clinical Internal Medicine
Objective to investigate the possible impact of the polymorphism in 5A/6A MMP-3 gene promoter on the risk of essential hypertension in Han Lanzhou area population.Methods 104 hypertensive patients(hypertensive group) and 102 normal persons control were recruited.Polymerase chainreaction followed by restrictionfragment length polymorphism(PCR-RFLP) was used to detect SNP-1171(5A/6A)in MMP-3 gene promoter region.Results The distribution of MMP-3 genotype was not significantly different between… Expand