Association between the functional polymorphism in the matrix metalloproteinase-7 promoter and susceptibility to adult astrocytoma.

@article{Lu2006AssociationBT,
  title={Association between the functional polymorphism in the matrix metalloproteinase-7 promoter and susceptibility to adult astrocytoma.},
  author={Zhongqiang Lu and Yimin Wang and Qingjun Zhang and Xiang-hong Zhang and Shuheng Wang and Huiling Xie and Yuehong Li and Baohua Jiao and Jianhui Zhang},
  journal={Brain research},
  year={2006},
  volume={1118 1},
  pages={6-12}
}
To study the association between the A to G transition at the -181-bp position in the promoter of matrix metalloproteinase-7 gene (MMP-7-181A/G) and susceptibility to adult astrocytoma, the MMP-7-181A/G polymorphism was genotyped by PCR-RFLP analysis among 221 adult astrocytoma patients and 366 healthy controls in a population of northern China. The result showed that the overall distribution of the MMP-7 genotypes among astrocytoma patients and healthy controls was significantly different (P<0… CONTINUE READING

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