Association between the density of mossy fiber sprouting and seizure frequency in experimental and human temporal lobe epilepsy.

Abstract

PURPOSE If the sprouting of granule cell axons or mossy fibers in the dentate gyrus is critical for the generation of spontaneous seizures in temporal lobe epilepsy (TLE), one could hypothesize that epileptic animals or humans with increased sprouting would have more frequent seizures. This hypothesis was tested by analyzing the data gathered from… (More)

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@article{Pitknen2000AssociationBT, title={Association between the density of mossy fiber sprouting and seizure frequency in experimental and human temporal lobe epilepsy.}, author={Asla Pitk{\"a}nen and Jari Nissinen and Katarzyna Lukasiuk and Leena Jutila and Leo Palj{\"a}rvi and Tuuli Salmenper{\"a} and Kari O Karkola and Matti Vapalahti and Aarne Ylinen}, journal={Epilepsia}, year={2000}, volume={41 Suppl 6}, pages={S24-9} }