Association between the apolipoprotein B signal peptide gene insertion/deletion polymorphism and male infertility.

@article{Peterlin2006AssociationBT,
  title={Association between the apolipoprotein B signal peptide gene insertion/deletion polymorphism and male infertility.},
  author={Borut Peterlin and Branko Zorn and Marija Volk and Tanja Kunej},
  journal={Molecular human reproduction},
  year={2006},
  volume={12 12},
  pages={777-9}
}
In male mice heterozygous for a null apolipoprotein B (apoB), allele infertility was noticed. These data led us to investigate a possible role of APOB gene polymorphism and male infertility in humans. In this case-control study, we searched for an association between the insertion/deletion (I/D) polymorphism of the APOB gene and male infertility in 560 Slovene Caucasian men. The study group consisted of 310 infertile patients: 115 with azoospermia and 195 with oligoasthenoteratozoospermia (OAT… CONTINUE READING
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