Association between the Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor Gamma 2 and Inflammatory Bowel Disease: A Meta-Analysis

@inproceedings{Zhang2012AssociationBT,
  title={Association between the Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor Gamma 2 and Inflammatory Bowel Disease: A Meta-Analysis},
  author={Zhi-feng Zhang and Ning Yang and Gang Zhao and Liang Zhu and Li Wang},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor, has been implicated playing a role in the development of inflammatory bowel disease (IBD). However, previous studies evaluating the association between the PPARγ2 Pro12Ala polymorphism and IBD are inconsistent. We performed a meta-analysis to determine whether the PPARγ2 Pro12Ala mutation was associated with the presence of IBD. METHODS AND FINDINGS Electronic databases were searched for case-control… CONTINUE READING

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